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題名：安寧療護患者的抗憂鬱劑選擇及共同照護
書刊名：安寧療護
作者：王律凱／林益卿／蔡佩渝／黃馨葆
作者(外文)：Wang, Lu-kai／Lin, I-chin／Tsai, Pei-yu／Huang, Sin-bao
出版日期：2015
卷期：20:1
頁次：頁24-35
主題關鍵詞：安寧療護；共同照護；重度憂鬱症；抗憂鬱藥劑；Hospice；Cancer；Combined care；Major depression；Antidepressants
原始連結：連回原系統網址new window
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  • 被引用次數被引用次數:期刊(0) 博士論文(0) 專書(0) 專書論文(0)
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  • 共同引用共同引用:10
  • 點閱點閱:36
安寧療護患者合併重度憂鬱的情形是常見的症狀，如果患者符合DSM-5的重鬱症狀，則抗鬱劑的治療是建議的，根據有限的文獻整理，重點如下：1)安寧療護的患者對於抗鬱劑選擇建議使用專一性較好的藥物，對於副作用減少以及可接受度(acceptability)是較有利的。2)合併重度憂鬱的安寧療護患者，則建議與精神專科(psychiatrist)以及神經內科專科(neurologist)共同照護，才能得到最好的療效。
Depression is a common symptom in palliative care patients. If terminal stage palliative patients suffer from major depression, use of antidepressants is recommended. We reviewed the recent articles to summarize the choice of antiderpressants for palliative patients: 1) Use of single highly selective antidepressant is recommended for palliative patients, because of reduced side effect and better acceptability. 2) Anxious hospice patients, avoid activating agents, use ADs with anti H1 activity will be better. Fatigue patients, prefer NE/DA agents than 5HT ones. Poor pain control patients, prefer SNRIs than SSRIs. Breast cancer, avoid ADs inducing PRL. Colon cancer, avoid ADs with anticholinergic activity. Nausea patients, avoid starting SSRIs togheter with chemotherapies. Hyporexia patients, use AD with anthistaminic activity or benzamides substituted. 3) Combined care with psychiatrist and neurologist for palliative patients with major depression disease will have better efficacy and acceptability.
期刊論文
1.Akechi, T.(2012)。Psychotherapy for depression among patients with advanced cancer。Jpn J Clin，12，1113-1139。  new window
2.Torta, R.、Miniotti, M.、Leombruni, P.(2012)。Antidepressants in oncology: reason and choice。Neuropathol Dis，1(2)，179-204。  new window
3.Massie, M. J.(2004)。Prevalence of depression in patients with cancer。Journal of the National Cancer Institute Monographs，2004(32)，57-71。  new window
4.Harter, M.、Baumeister, H.、Reuter, K,(2007)。Increased 12-month prevalence rates of mental disorders in patients with chronic somatic diseases。Psychother Psychosom，76，354-360。  new window
5.Dalton, S. O.、Laursen, T. M.、Ross, L.(1973)。Risk for hospitalization with depression after a cancer diagnosis: a nationwide, population-based study of cancer patients in Denmark from 1973 to 2003。J Clin Oncol，27，1440-1445。  new window
6.Prieto, J. M.、Blanch, J.、Atala, J.(2002)。Psychiatric morbidity and impact on hospital length of stay among hematologic cancer patients receiving stem-cell transplantation。J Clin Oncol，20，1907-1917。  new window
7.Pinquart, M.、Duberstein, P. R.(2010)。Depression and cancer mortality: a meta-analysis。Psychol Med，40，1-14。  new window
8.Lo, C.、Zimmermann, C.、Rydall, A.(2010)。Longitudinal study of depressive symptoms in patients with metastatic gastrointestinal and lung cancer。J Clin Oncol，28，3084-3089。  new window
9.Patten, S. B.、Barbui, C.(2004)。Drug-induced depression: a systematic review to inform clinical practice。Psychother Psychosom，73(4)，207-215。  new window
10.Reyes-Va'zqueza, C.、Prieto-Go'meza, B.、Dafny, N.(2012)。Interferon modulates central nervous system function。Brain Res，1442，76-89。  new window
11.Dutta, V.(2011)。Chemotherapy, neurotoxicity, and cognitive changes in breast cancer。J Cancer Res Ther，7(3)，264-269。  new window
12.Holland, J. C.、Alici, Y.(2010)。Management of distress in cancer patients。J Support Oncol，8，4-12。  new window
13.Patten, S. B.、Williams, J. V.、Lavorato, D. H.、Bulloch, A. G.、Currie, G.、Emery, H.(20130607)。Depression and painful conditions: patterns of association with health status and health utility ratings in the general population。Qual Life Res，23(1)，363。  new window
14.Frewen, P. A.、Dozois, D. J.、Lanius, R. A.(2012)。Assessment of anhedonia in psychological trauma: psychometric and neuroimaging perspectives。Eur J Psychotraumatol，3。  new window
15.Torta, R.、Leombruni, P.、Borio, R.(2011)。Duloxetine for the treatment of mood disorder in cancer patients: a 12 week casecontrol clinical trial。Hum Psychopharmacol，26，291-299。  new window
16.Sharpley, C. F.(2010)。A review of the neurobiological effects of psychotherapy for depression。Psychotherapy，47(4)，603-615。  new window
17.Akechi, T.、Okuyama, T.、Onishi, J.(2008)。Psychotherapy for depression among incurable cancer patients。Cochrane Database Syst Rev，16(2)。  new window
18.Fournier, J. C.、DeRubeis, R. J.、Hollon, S. D.(2010)。Antidepressant drug effects and depression severity: a patient-level meta-analysis。JAMA，303(1)，47-53。  new window
19.Kanzler, K. E.、Bryan, C. J.、McGeary, D. D.(2012)。Suicidal ideation and perceived burdensomeness in patients with chronic pain。Pain Pract，12(8)，602-609。  new window
20.Lydiatt, W. M.、Denman, D.、McNeilly, D. P.(2008)。A randomized, placebo-controlled trial of citalopram for the prevention of major depression during treatment for head and neck cancer。Arch Otolaryngol Head Neck Surg，134，528-535。  new window
21.Reilly, C. M.、Bruner, D. W.、Mitchell, S. A.(2013)。A literature synthesis of symptom prevalence and severity in persons receiving active cancer treatment。Support Care Cancer，21(6)。  new window
22.Stenman, E.、Lilja, A.(2013)。Increased monoaminergic neurotransmission improves compliance with physical activity recommendations in depressed patients with fatigue。Med Hypotheses，80(1)，47-49。  new window
23.Davis, M. P.、Kirkova, J.、Lagman, R.(2011)。Intolerance to mirtazapine in advanced cancer。J Pain Symptom Manage，42(3)，4-7。  new window
24.Steams, V.、Johnson, M. D.、Rae, J. M.(2003)。Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine。J Natl Cancer Inst，95(23)，1758-1764。  new window
25.Houlihan, D. J.(2004)。Serotonin syndrome resulting from coadministration of tramadol, venlafaxine, and mirtazapine。Ann Pharmacother，38(3)，411-413。  new window
26.Cipriani, A.、Furukawa, T. A.、Salanti, G.(2009)。Escitalopram versus other antidepressive agents for depression。Cochrane Database of Systematic Reviews，2。  new window
27.Cipriani, A.、Barbui, C.、Salanti, G.、Rendell, J.(2009)。Sertraline versus other antidepressive agents for depression。Cochrane Database of Systematic Reviews，2。  new window
28.Chaturvedi, S. K.、Maguire, P.、Hopwood, P.(1994)。Antidepressant medications in cancer patients。Psychooncology，3，57-60。  new window
29.徐翠霞、蕭淑純、孔憲蘭、賴允亮、賴明亮、陳慶餘、曹朝榮、陳榮基、周希諴、黃信彰、莊榮彬(20070500)。2005年臺灣安寧共同照護計畫實施之成效。安寧療護，12(2)，129-142。new window  延伸查詢new window
圖書
1.American Psychiatric Association(2011)。Diagnostic and statistical manual of mental disorders。Washington, DC：American Psychiatric Association。  new window
2.(200904)。MeReC Monthly。  new window
圖書論文
1.Li, M.、Boquiren, V.、Lo, C.(2011)。Depression and anxiety in supportive oncology。Supportive Oncology。Philadelphia：Elsevier。  new window
 
 
 
 
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