本研究的目的是利用交互式多媒體教學系統(IMI) 作為國中學生學習細胞分裂(含有絲分裂與減數分裂)之學習工具，並探討學生使用概念圖以及學習成就水準對上述學習工具的成效。而研究結果發現：國中學生利用IMI系統來學習細胞分裂的學習過程中，若能配合使用概念圖時，效果則更佳。在精心設計的軟體中學習，國中學生學業成就的水準在IMI學習成就上，無顯著差異存在。IMI系統的學習，對學生的學習保留，有良好效果。大部分國中學生喜愛兩個人一起學習。

　　　　　This paper describes how manipulating Interactive Multimedia Instruction (IMI) system influences junior high school students' learning about cell division that includes meiosis and mitosis, and to explore the different influences of concept mapping and academic achievement on the IMI system effectiveness. The following results were found: First, significant and positive learning effect were found among junior high school students who learned cell division through IMI system. Second, if IMI system incorporates concept mapping in the learning process, the learning effect will be reinforced. Third, students with different academic achievement levels learning through well-designed software of IMI system appear to acquire the same learning achievement. Fourth, learning through IMI system benefits learning retention. Last, most junior high school students enjoy studying with a friend.