Since the new century,with the rise of interdisciplinary research,philosophical method is more applied to linguistics,cultural studies,and medio-translatology. From the relationship between philosophy and medio-translatology,the cognitive dimension and significance of the Marxist philosophy in the new era for the translation and reception of national culture is investigated. Research viewpoints are given as follows:First,the contradiction theory of Marxist philosophy dialectics decides the need for the translation and reception of national culture; Second,in practice,what is supposed to achieve during the process of translation and reception is the opposition and balance between binary oppositions and philosophy,that is,the opposition and balance between literal translation and free translation,the opposition and balance between cultural migration and transformation,as well as the opposition and balance between the science and artistry; Third,the theory on translation and reception of national culture is evolving,and it is changing from pragmatism to the philosophical interpretation of the transition. The study integrates philosophy, linguistics, cultural studies, and medio-translatology as one, providing a multi-disciplinary integration paradigm. The Theory on the translation and reception of national culture is evolving,and it is changing from pragmatism to philosophical interpretation. The study unites philosophy, linguistics, cultural studies, and medio-translatology as one; therefore,it provided a multi-disciplinary integration paradigm.