Zhuang Zi employed Lao Zi’s argumentative framework to construct his theory about the genesis of the universe, highlighting “qi”, the interface of the elements of the universe. The article is made to review the development of Zuang Zi’s Qi-hua (Qi transformation) cosmology in the Pre-Qin Period and the Han Dynasty, describing the guidelines of the resulting Wei and Jin metaphysics and aesthetics. Then on the basis of Liu Shao’s Ren Wu Zhi (Personal Character), Ji Kang’s appearance-sprite theory, and Guo Xiang’s natural-endowment theory, the writer goes on the discus Tsao Pi and Liu Xie’s reviews about the literary criticism of the Wei and Jin Dynasties, especially the one of the Jian An Period-“qi as the main thing in literature” and kangkairenqi-to reveal the theoretical meanings of the concept, “qi”, in the metaphysics and aesthetics of the Wei and Jin Dynasties.