The current study explored the influences of parent-child relationship and empathy on social creativity and the mediating role of friendship quality on such effects. A series of questionnaires, including the Social Creative Tendency Questionnaire for Children,Closeness to Parents Scale, Interpersonal Reactivity Index-C(IRI-C), and Friendship Quality Questionnaire(FQQ), were used to survey 588 middle school students. The results was showed as follows: 1) mother-child relationship, father-child relationship, and empathy directly predicted social creativity of adolescents; 2) friendship quality mediated the prediction of social creativity by mother-child relationship and empathy. The present study reveals various mechanisms on how parent-child relationship and empathy impact the social creativity of the adolescents, which would provide parents and educators with valuable insights on promoting the creativity of adolescents.