The main purpose of this study was to investigate the practice and difficulties of the cross-categorical itinerant teachers in Hualien. The study conducts two questionnaires to both itinerant teachers and general education teachers. Individual interviews were conducted to thirteen itinerant teachers. The main findings are: 1.The themes that influenced teachers' working include traveling insurance, equipment and facility, lacking research, caseloading, and cooperation between itinerant teachers and general education teachers. 2.The expectation gaps between itinerant teachers and general education teachers are regulation of curriculum and teaching materials, students' guidance and consultation. 3.The interview findings are including the itinerant teachers spent most of time in direct teaching, executing IEP regulation, lacking assessment drills. The most difficulties for itinerant teachers are teaching abilities of cross-categorical handicapped students, shortage of collegial support, and caseloading. According to the research results and findings, concrete and practical suggestions were made.