The article describes a nursing process of a lung cancer with bony metastases patient receiving total hip replacement. Communications, interviews, chart reviews and the Gordon 11 functional assessment tool were applied to collect subjective and objective data from August 22 to August 28 in 2007. The patient was confronted with anxiety, grieving, acute pain, and impaired physical mobility. During the nursing process, individualized nursing care provided by giving pain-released methods and offering a project of rehabilitation excises to recover patient’s mobility. In addition, caring, listening and accompanying were provided to assist the patient facing the fear of death and to reduce responses from grieving. This nursing experience of holistic care may be shared with other healthcare professionals. It is expected the nursing staff can not only develop nursing intervention to decrease physically discomfort but also improve psychological distress for patients with the same suffering.