This article has three goals: first, to compare gender differences on personal adjustment, second, to analyze regional differences on general adjustment, and third, to introduce content analysis and case studies as a guideline for applications in counseling. 965 junior high school students who were drawn form the northern, middle, and southern regions of Taiwan completed the sentence completion measure. T test, one-way ANOVA, content analysis, and case studies were employed to analyze the data. The results indicated: (1)that gender differences on personal adjustment were significant, boys reporting more positive responses and less negative responses than girls; (2)that regional differences on general adjustment were also signification, students from the northern region showing lower positive responses than those from middle and southern regions; (3)that gender differences were salient in self-confidence, family involvement, and emotional coping strategies through content analysis; and (4)that regional differences existed in aspects including concerns for environmental pollution, family involvement, academic achievement, and political attitudes. The implications for guidance were discussed.