Objectives: The aims of this study were to determine the level of understanding and attitude changes of staff in the case hospital before and after implementation of Balanced Scorecard (BSC), as well as to discuss the problems encountered during that implementation. Methods: This study uses Mixed Methods including questionnaire surveys, in-depth interviews, and participant observation to compare and verify the results from both the qualitative and quantitative data in order to increase trustworthiness and credibility. A total of 339 copies of questionnaires were distributed before and after the implementation of BSC, and the effective recovery rates were 85.84% and 86.14% respectively. Results: Findings from the pretest questionnaires show that rank of the staff member made a significant difference in terms of understanding. With regard to attitude, the rank and education level of staff members showed statistically significant. Findings from the posttest questionnaires showed that rank, gender, age, and education level made significant differences in terms of understanding. With regard to attitude, the education level of the staff members showed statistically significant. After training, staff members understood BSC better and had a more positive attitude. On multiple parameters, the determination and support of supervisors were key elements in promoting a positive attitude on the part of nursing staff. Previous experience with BSC, promoting BSC as part of daily activities, group meetings, and the assistance of experts reduced the difficulties in implementing BSC for the staff. Conclusions: With multiple research methods, we were able to clarify the questions which arose during implementation of BSC. Support and participation of supervisors were key factors in promoting BSC. With encouragement, trainings, and open channels of communication, the process of implementation went much more smoothly.