This article discusses an important subject about colonial medicine. That is to analyze a later developing imperialistic country-Japan in the last period of 19(superscript th) century how to introduce the experience of the European tropical acclimatization to protect the emigrants Japanese health, and how to apply the different racial discourses to accentuate the ability of Japanese tropical colonization superior than the European. This paper point out the concept of tropical acclimatization was a kind of governmental technology to understand and control the colony. Its function of this concept was not only to define and discourse colonized the other, but also to consolidate self-identification of the colonizer and stimulate the colonial competition. This paper also analyzes the tropical acclimatization of Japanese in Taiwan underwent some different stages. In the early period under Japanese Rule, Colonial Government paid attention to investigate or articulate the characteristic of Taiwan's environment. And in order to monitor the conditions of Japanese acclimatization, Colonial Government took great concern with the health condition of Japanese army. In the meantime, depending on the development of tropical medicine, the environment was to be separated into two factors, climate and diseases. And because Colonial Government concentrated on controlling the diseases, effectively improve the problem of acclimatization. After 1910s, Colonial Government turned to discipline the healthy practices of Japanese teenager who because of born at Taiwan, was called ”Wan-Sen”. Colonial Government applied the healthy investigation of the body at school to manipulate scientific and mathematic management of the body, and in the long run, demonstrated the constitutions of Wan-Sen to become acclimatizing tropical environment. From the stead growing of Wan-Sen's population displayed the accomplishment of Japanese tropical acclimatization. In conclusion, this paper points out, from 19(superscript th) century, Europeans were afraid to immigrating to the tropics. They thought if staying there longer, there were probable to induce the degeneration of the race. Comparatively, Japanese in Taiwan announced and demonstrated the efficiency of tropical acclimatization, displayed their ability of colonial competition very differently. The efficiency of Japanese tropical acclimatization mainly depended on tropical medicine, measurements of tropical hygiene, and discourses of mixed race.