Information literacy enhancement is an important job for current general education in universities. Information literacy is a capability, via appropriate channels; it can collect information, screen information, integrate information, evaluate information, create information, and use information. Information literacy is used for effective communications, interactions and problem solving; it includes five capabilities, information requirement, information obtainment, information use, information assessment, and information ethics. Moreover, information literacy involves six areas, information skills, media reading, information reading, information society, information ethic, and information security. Currently, information network technology is developed and clouding computing environment is getting matured. Internet search engines, electronic databases / books and different areas professional / community websites can provide diverse and rich information. Clouding computing environment can support capabilities of information storage, information process and information use. Moreover, via related area professional / community website communications, we can evaluate information with experts in different areas. Therefore, in the E generation, we will be able to achieve maximum effectiveness of information literacy enhancement if we can make the best use of information technology, follow information ethics and fulfill information security.