The purpose of this study was to explore the maturity of clinical nurses' career development and the relationship between nurses' career development and their intent-to-stay. The Clinical Nursing Career Development Inventory (CNCDI) was used to measure nurses' career development. 612 subjects were recruited from two medical centers. 532 questionnaires were completed with a response rate of 86.9%. Results showed that the career development maturity of the clinical nurses was moderate. Several factors were found to be significantly associated with the career development maturity for the two hospitals, including personal factors, such as age, educational level, working experience, working departments, and interest in nursing; and family factors, such as marital status, children and family members at home needing personal care. But organizational factors, such as the clinical ladder system and training programs were significant only in one hospital. The most important finding in the study was the significantly positive correlation between nurses' career development and their intent-to-stay.