Purchasing absolutely had direct effect on the enterprise profit. The professional competence of assistant purchasing manager was indispensably to the enterprise. The main purpose of this research was to construct the professional competence domain and index of assistant purchasing manager in international hotel. First, the structure of professional competence questionnaire was made by depth interview and literature review, and used purposive sampling to investigate. Then the research used Fuzzy Delphi Method to choose the important item of professional competence and Analytic Hierarchy Process to indentify the professional competence domain, index, items and weight of assistant purchasing manager in international hotel. This study used the weight analysis of professional competence to analyze the importance and rank interpretation. The results were the following: in total domain, general professional competence was more important than technique professional competence; weight index in each domain, the most important professional competence were problem-solving and purchasing management ability. Heavy-weight indices could be used in designing human education course and teaching material in international hotel. The study also suggested international hotel could recruit new staff outside or promote staff inside the organization to obtain superior assistant purchasing manager.