This study investigates the effect of twelve self-designed kid-song teaching activities on inter-person interactions in preschool inclusive classes. Two subjects were chosen from preschool inclusive classes in Hualien area. The experimental desigh is based on A-B-A test, “self-designed kid-song teaching activity inter-person interactions evaluation list”, and “self-designed kid-song teaching activity curriculum evaluation list”. Based on the research results, we found: (1) Self-designed kid-song teaching activity can improve the focusing behaviors such as “eyecontact”, and “order obedience”. (2) Self-designed kid-song teaching activity can increase the frequency of inter-person communication behaviors like “praise others”, and “talk to others”. (3) The cooperative behaviors such as “cooperate with other” and “take in turns” were improved. (4) The frequency of negative inter-person interactions was decreased. Analysis and further discussion were processed based on results of this study. Suggestions for future curriculum desigh\ned of preschool inclusive classes were provided.