The main goal of this research is to analyze the learning effectiveness of Economics courses by designing the course according to the characteristics of the young generation. Multiple-learning approaches and statistical analysis on learning outcomes are adopted. Learning effectiveness refers to improving students' economic concepts, learning interests, and ability to analyze economic issues. I aim to realize how learning effectiveness is related to the multiple-learning approach for a class of size 100 students. The results indicate that multiple teaching approaches positively relate to learning effectiveness. No significant difference in learning scores is found regardless of the student's economic knowledge. Similar findings are shown for the students from different schools who took the course. The better the students' learning motivation is, the better their learning outcomes will be. So teachers must enhance students' motivation to learn economics. The learning effectiveness varies across teaching approaches. Lecturing and PPT handouts still seem necessary for teaching Economics courses, having the largest effects on improving students' economic concepts and their ability to analyze economic issues. Adopting approaches such as Google Forms questionnaires and DVD videos significantly affect students' learning interests. Economic case study methodology improves students' ability to analyze economic issues. If the frequency of the methods mentioned above is selected or adjusted according to the composition of students, such as school and gender, the results should be more effectively improved.