Core Self-Evaluations Scale(CSES), Children’s Hope Scale(CHS) and Adolescent Students’ Life Satisfaction Scale(ASLSS)were used by 934 adolescent students to explore the relationship among core self-evaluations, hope and life satisfaction and the mediating effect of hope between core self-evaluations and life satisfaction in adolescents. The results showed that: 1) Significant positive correlation existed among core self-evaluations, hope and life satisfaction in adolescents; 2) Core self-evaluations positively influenced life satisfaction directly, and also through hope indirectly, and hope played a mediating effect in the relationship between core self-evaluations and life satisfaction in adolescents.