The relationship between public opinion and public policy is an intriguing and important research topic. In a democratic society, leaning and finding public opinion is indispensable in the process of policy formulation. This paper begins with a c1arificationof the concept of public opinion, lists all the methods of measurement, and examines the potential problems and limitations of these methods. In order to avoid the unduly influence on the policy-making process by the minor, manipulated, and distorted public opinion, this paper suggests using professional poll and deliberative poll to detect genuine and quality public opinion. In the history of mankind, due to various limitations and problems imposed by the measurement of public opinion, whether or not policymaking should totally depend upon public opinion has aroused concerns and debates in the development of democracy theory. By depicting a number of well-known policy examples and statesmen, this paper indicates that public opinion and public policy is not and should not be a simple chicken-and-egg causal relation. "Whatever people desire is always in my heart" has fundamental value in a democracy. However, public opinion is often manipulated and sometimes problematic. This later statement, though not very pleasant to hear, is essential and important to mature citizens, first-rate policy analysts and decision-makers in their perception and evaluation of public opinion. This paper sincerely expects our policy analysts and decision-makers have political wisdom and moral courage to make policy choices based on not only public opinion but also public interest and public justice.