Christianity and Buddhism is the major force behind Taiwan's social welfare, meeting the service needs for people under social change. Their contribution is obvious to all, but both meet great challenges of survival as well. Confused with the value of cultural fault zone in the material and commercialized social atmosphere, various relief activities are mixed with disorder of human disputes and social chaos, deteriorating the mutual adaption of conversing energy between the sacred and the secular. Influenced by the reality, they are often faced with the possible crisis of deterioration and collapse. While religious social care has its positive value and significance, it may lead to secularization when increasingly concerned about the secular affairs of life, and hence deviates from its original divine faith connotation. This kind of cultural phenomenon, the conflict between the sacred and the secular, should be tackled seriously through self-depth reflection when religions actively promote social care. As religious societies develop side by side with social secularization, they may get a lot of missionary convenience and advantages; however, they are also faced with a variety of differentiation and challenges, which damages or misleads the sacred character of religion. Since there are few academic discussions in this regard, this paper aims to explore how Christianity and Buddhism, both faced with the challenge of secularization in reality, get back to the divine moral principles to adapt to the changing times. As the basis of the dialogue, whether Christianity and Buddhism are ready for this kind of harsh cultural challenges through value adjustment and method renovation is also discussed.