This essay analyzes Ruan Ji's perspective on Xin and Xing (mind and nature.) as follows: Xing is original nature of human, endowed by Qi and has its positive value. Xin is the trigger of Qing, which can be accord or disaccord with nature. Xin should act as the master of Qing, a key to where Qing goes. Only when Xin does the good job, Qing will be triggered accordingly. Thus the cultivation of Xin or Shen was demanded and Qi was considered as the intermediary of the whole procedure. "Stabilize of Mind and Human Nature" can be took as an abstract of Ruan Ji's concept of mind and nature which is the common foundation of his various works.