Petrochemical industry is one of the most important primary industries in Taiwan. Products of this industry comprise headstream basic parts, middle stream medial parts, and down stream processing wares. According to Industrial Development Bureau (IDB), the total production value of petrochemical industry has exceeded 12000 hundred millions NT dollars, with the percentage standing at approximately 23% of the whole manufacturing industry. Therefore, it enormously affects the domestic economy. In recent years, global demand on petroleum chemicals is growing. The ongoing attempt to carry out the tenth five-year plan from the mainland China specifically and especially stimulates the rapid growth of the petrochemical industry. Building a petrochemical industrial park is becoming the priority construction across the strait. Currently, to ensure the plant-building efficiency, most petrochemical plant constructions adopt the design-build mode. In the past, on the contrary, since there were no formal and strict criteria for plant builder selection, quality of builders differs tremendously, such as producing flaws in certain design cases, making untoward operations, and creating tremendous cost in maintenance and resulting in huge waste. In light of the unsuccessful past domestic plant-building experiences, selecting a reliable design-builder is a key factor for petrochemical plant to finish construction without a hitch. This paper focuses on plant-building design-builder selection criteria for the petrochemical industry and analyzes in depth all relevant documentations, either domestic or abroad, regarding scholars, institutes, and public projects, and other related writings concerning plant-building practices from a certain petrochemical firm in Taiwan to discuss the correlations of petrochemical plant-building factors, builder selection factors of public projects, and design-builder selection criteria for the petrochemical plant construction. Based on the correlations established, expert interview is conducted, questionnaire is designed, and factor analysis is conducted to establish the criteria hierarchy. Then, the Analytic Hierarchy Process (AHP) is applied to determine each criterion weight and to establish a strict but feasible selection criteria mechanism. The results of this study may serve as a reference for managers of petrochemical industry in choosing the best plant-builder.