“Qi Wu Lun” (the theory of the equality of all things) makes an epistemological layered analysis about the cognitive function that leads to human beings’ greed and obsession with materials, so as to anatomize what causes such preconceptions. Then, after examing human beings’ cognitive and mental greed, obsession and competition, we will take the vantage point of onto-cosmology to identify and analyze the confines and difficulties encountered by people’s epistemological and speculative knowledge. Consequently, we will illustrate the dynamics and truth of the universe and life, direct human beings to transcend the mire of relative knowledge and the confines of prejudices, and then obtain the metaphysical wisdom and the wisdom to get along in this world. At the age of fifty-six, Wang Yang-ming (1472~1528) wrote the article, “The Great Learning,” proposing the doctrine of “Yi Ti Zhi Ren” (the innumerable things are regarded as one substance by jen). “Yi Ti Zhi Ren” is about how to realize the innate good knowledge and correspond infinitely with the whole world of being. In terms of ontology, Zhuang Zi’s “Tao” from “the thoroughness of Tao is One” is the fundament that governs the universe and all things and therefore an objective existential approach. Though Wang’s idea about “one substance by Jen” also originates in the everlasting great virtue of the heavenly mandate, obviously, what he constructs is a moral metaphysics that integrates the heaven, the people and life. In Wang’s opinions, human beings have their humanistic care about the world and are obligated to participate in it; on the other hand, Zhuang Zi corresponds with the spirit of heaven and earth, transcends the material world and enjoys the infinite beauty of the world during his finite life. Zhuang Zi’s view of human beings is oriented toward the doctrine of form and spirit, while Wang Yang-ming’s view about human beings is oriented toward the mind-nature theory of “innate good knowledge.” These two philosophers construct the two grand light houses of Chinese philosophy respectively as a man of great wisdom and a man of great kindness, inspiring and directing numerous people who are lost on the path of life and traveling between these two light houses.