The major purpose of this study was to explore how to integrate the information technology into Calculus teaching in university and to assess its effectiveness upon the Calculus learning of the National Formosa Universit students.The quasi- experimental design was used to compare the effect of the information technology Integrated Instruction and traditional method.The 106 university students,who take in the Calculus course,were invited to participate in the study. In this research,A class of 53 students were picked up randomly as the experimental group,while the other class was the control group.After eight-week treatment,data were collected in the study.The result revealed that(1)there are no distinguished differences in parents , education background and family economy.(2)The results showed both the control and the experimental groups had significantly differences in learning anxiety, learning time. (3)In terms of the experimental groups,there were significant differences between pre-scale and post-scale on learning time,management information.(4) In the terms of the control group with the trational teaching,there were significant differences between pre-scale on learning anxiety.(5)The achievement test of Calculus in the experimental group were significantly better than the control group.