Objectives: The purpose of this study is to assess the confirmatory factor analysis of body image and self-esteem by structural equation modeling. We also conducted path analysis to see the model fitness between body image, self-esteem on dermal satisfaction and the intention of non-invasive cosmetic medical intentions. Method: 422 valid samples were collected from the employees of one hospital. The intention of non-invasive cosmetic medical treatments was measured by reliable questionnaires about body image and self-esteem, and by the dermal satisfaction scale designed for the study purpose. LISREL 8.71 was used to assess the model fitness. Results: The indices of the model fitness were acceptable. Body image that was correlated with self-esteem was distinguished into two dimensions of appearance evaluation and appearance orientation (r=.34; .30). Appearance evaluation was positively correlated with dermal satisfaction (r=.27), and appearance orientation was positively correlated with the intention of noninvasive cosmetic medical treatments (r=.17). According to the path analysis, appearance orientation and dermal satisfaction has taken a direct effect on people’s intention for non-invasive cosmetic medical treatments (path coefficients β=.19; -.39, p<.001). However, through dermal satisfaction, appearance evaluation and self-esteem produced an indirect outcome to the non-invasive cosmetic purposes. Conclusion: The appearance evaluation of body image is a sensual judgment that regards to one's own appearance. It will influence a person's sense of satisfaction towards physical appearance. The appearance orientation shows the psychological importance to individual appearance. Only strong motivation would initiate the behavior and intention; consequently, to seek for non-invasive cosmetic medical treatments.