Recently, life education is paied much attention because of many social affairs. After Grade 1st-9th Curriculum Alignment, the issue of life education is belonged to the Integrative Activities Learning Area. In fact, each teacher must own the professional knowledge and skills in order to infuse life education into the curriculum. How to teach life education? The topic method and the infusion method are adopted frequently. The topic method must use extra time. However, the infusion method is an efficient method. The purpose of this research is providing the principles and the practice of the infusion curriculum designing of life education for teachers in order to reach the goals of life education. First, the concept of life education is cleared. Secondly, the principles of the infusion curriculum designing are stated. Thirdly, the teaching plan of the Literary Learning Are is designed for an example in the secondary school. Last, the outcomes and suggestions are offered.