The purpose of this study was to realize the feasible strategies and the impeditive factors for elementary teachers to innovate knowledge and compare different viewpoints about feasible strategies and the impeditive factors in the category subject's background. The subjects were teachers who serviced at the elementary schools in Tainan county. The two research methods employed by this study were interviewing with teachers and distributing questionnaires. The subjects interviewed were four teachers at elementary schools in Tainan county. A total of 750 questionnaires were mailed out in a purposive sampling way, of which 669 were completed and considered as valid questionnaires. The return rate for the completed questionnaires was 93.44%. Data, collected through questionnaires was analyzed by percentage statistics, T-test, and one-way ANOVA to provide evidence in support of the hypothesis. The result of the research was as follows: The feasible strategies for innovating knowledge were enriching new knowledge, benchmarking, discussing, brainstorming, teaching research and experimental teaching, developing abilities to be agile and flexible, and supplying enough motives from school. The impeditive factors for innovating knowledge were few learning opportunities, an unwillingness to be innovative, low learning motivation, inabilities to adjust to changing circumstances, and differences among knowledge.