In order to enhance the learning of emergent science and technology at Taiwan, the Department of Science Education in National Science Council initiated a so called “Project of High Scope” since 2005. It emphasizes the establishment of the partnership between senior high schools and universities or research organizations to improve the quality of teaching in science through the development of new school-based curriculum. The school-based curriculum is intended to actively promote the “bottom up” curriculum development model which empowers teachers to work out professional autonomy. However, in order to reduce the gap between theory and practice, it is expected that teachers can deeply theorize the purposes of curriculum and actualize their ideal of instruction by themselves. The purpose of this study is to investigate teachers’ belief and value of the curriculum as well as their understanding of the curriculum development. The study looks into teachers understanding of curriculum content, curriculum development process, teacher self vs. students, as well as the school context. The study applies case study techniques such as observation, interview and archive analysis to come to a holistic interpretation of the curriculum development from teacher’s perspectives. The results of the study will provide suggestions for the further curriculum development of the case school as well as the improvement of the quality of “High Scope Project”.